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An analysis of the molecular origin of osmolyte-dependent protein stability

Protein solvation is the key determinant for isothermal, concentration-dependent effects on protein equilibria, such as folding. The required solvation information can be extracted from experimental thermodynamic data using Kirkwood-Buff theory. Here we derive and discuss general properties of prote...

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Detalhes bibliográficos
Main Authors: Rösgen, Jörg, Pettitt, B. Montgomery, Bolen, David Wayne
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203340/
https://ncbi.nlm.nih.gov/pubmed/17327389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062671607
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