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A molecular mechanism for osmolyte-induced protein stability
Osmolytes are small organic compounds that affect protein stability and are ubiquitous in living systems. In the equilibrium protein folding reaction, unfolded (U) ⇌ native (N), protecting osmolytes push the equilibrium toward N, whereas denaturing osmolytes push the equilibrium toward U. As yet, th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564065/ https://ncbi.nlm.nih.gov/pubmed/16968772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606236103 |
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