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Comparative molecular dynamics analysis of tapasin-dependent and -independent MHC class I alleles
MHC class I molecules load antigenic peptides in the endoplasmic reticulum and present them at the cell surface. Efficiency of peptide loading depends on the class I allele and can involve interaction with tapasin and other proteins of the loading complex. Allele HLA-B*4402 (Asp at position 116) dep...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2203297/ https://ncbi.nlm.nih.gov/pubmed/17242432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062568407 |
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