Peptide immunization in humans: a combined CD8(+)/CD4(+) T cell-targeted vaccine restimulates the memory CD4 T cell response but fails to induce cytotoxic T lymphocytes (CTL)

Immunization with short antigenic peptides represents a potential strategy to induce peptide-specific CTL in vivo. In this study, a synthetic vaccine consisting of an HIV-derived, HLA-A2.1-binding CTL epitope and a tetanus toxin-derived T helper epitope was evaluated for its capacity to induce pepti...

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Detalhes bibliográficos
Main Authors: BRANDER, C, CORRADIN, G, HASLER, T, PICHLER, W J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1996
Assuntos:
Rapid Publications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200486/
https://ncbi.nlm.nih.gov/pubmed/8697628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-725.x
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