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CD4 CTL, a Cytotoxic Subset of CD4(+) T Cells, Their Differentiation and Function

CD4(+) T cells with cytotoxic activity (CD4 CTL) have been observed in various immune responses. These cells are characterized by their ability to secrete granzyme B and perforin and to kill the target cells in an MHC class II-restricted fashion. Although CD4 CTLs were once thought to be an in vitro...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Takeuchi, Arata, Saito, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321676/
https://ncbi.nlm.nih.gov/pubmed/28280496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00194
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