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Mouse Naïve CD4(+) T Cell Isolation and In vitro Differentiation into T Cell Subsets
Antigen inexperienced (naïve) CD4(+ )T cells undergo expansion and differentiation to effector subsets at the time of T cell receptor (TCR) recognition of cognate antigen presented on MHC class II. The cytokine signals present in the environment at the time of TCR activation are a major factor in de...
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Publicado no: | J Vis Exp |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MyJove Corporation
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4541570/ https://ncbi.nlm.nih.gov/pubmed/25938923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52739 |
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