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Mouse Naïve CD4(+) T Cell Isolation and In vitro Differentiation into T Cell Subsets

Antigen inexperienced (naïve) CD4(+ )T cells undergo expansion and differentiation to effector subsets at the time of T cell receptor (TCR) recognition of cognate antigen presented on MHC class II. The cytokine signals present in the environment at the time of TCR activation are a major factor in de...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Flaherty, Stephanie, Reynolds, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541570/
https://ncbi.nlm.nih.gov/pubmed/25938923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52739
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