CD40 Ligand-Mediated Interactions Are Involved in the Generation of Memory CD8(+) Cytotoxic T Lymphocytes (CTL) but Are Not Required for the Maintenance of CTL Memory following Virus Infection

CD8(+) cytotoxic T lymphocytes (CTL) play a key role in the control of many virus infections, and the need for vaccines to elicit strong CD8(+) T-cell responses in order to provide optimal protection in such infections is increasingly apparent. However, the mechanisms involved in the induction and m...

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Main Authors: Borrow, Persephone, Tough, David F., Eto, Danelle, Tishon, Antoinette, Grewal, Iqbal S., Sprent, Jonathan, Flavell, Richard A., Oldstone, Michael B. A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
Assuntos:
Viral Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC109974/
https://ncbi.nlm.nih.gov/pubmed/9696840
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