ロード中...
Different cofactor activities in γ-secretase assembly: evidence for a nicastrin–Aph-1 subcomplex
The γ-secretase complex is required for intramembrane cleavage of several integral membrane proteins, including the Notch receptor, where it generates an active signaling fragment. Four putative γ-secretase components have been identified—presenilin (Psn), nicastrin (Nct), Aph-1, and Pen-2. Here, we...
保存先:
| 主要な著者: | , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2003
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2199374/ https://ncbi.nlm.nih.gov/pubmed/12771124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304014 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|