Yüklüyor......

Different cofactor activities in γ-secretase assembly: evidence for a nicastrin–Aph-1 subcomplex

The γ-secretase complex is required for intramembrane cleavage of several integral membrane proteins, including the Notch receptor, where it generates an active signaling fragment. Four putative γ-secretase components have been identified—presenilin (Psn), nicastrin (Nct), Aph-1, and Pen-2. Here, we...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Hu, Yue, Fortini, Mark E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199374/
https://ncbi.nlm.nih.gov/pubmed/12771124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304014
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!