TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal

Developmental sympathetic neuron death is determined by functional interactions between the TrkA/NGF receptor and the p75 neurotrophin receptor (p75NTR). A key question is whether p75NTR promotes apoptosis by directly inhibiting or modulating TrkA activity, or by stimulating cell death independently...

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Bibliographic Details
Main Authors: Majdan, Marta, Walsh, Gregory S., Aloyz, Raquel, Miller, Freda D.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2001
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199335/
https://ncbi.nlm.nih.gov/pubmed/11756477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200110017
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