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Rac Mediates Cytoskeletal Rearrangements and Increased Cell Motility Induced by Urokinase-Type Plasminogen Activator Receptor Binding to Vitronectin

The urokinase-type plasminogen activator receptor (uPAR) is involved in the regulation of cell motility in a variety of cell types. We show here that expression of human uPAR in growing murine fibroblasts leads to a dramatic reorganization of the actin cytoskeleton. uPAR expression induces multiple...

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Sonraí Bibleagrafaíochta
Main Authors: Kjøller, Lars, Hall, Alan
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2001
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199201/
https://ncbi.nlm.nih.gov/pubmed/11257116
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