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Rac Mediates Cytoskeletal Rearrangements and Increased Cell Motility Induced by Urokinase-Type Plasminogen Activator Receptor Binding to Vitronectin

The urokinase-type plasminogen activator receptor (uPAR) is involved in the regulation of cell motility in a variety of cell types. We show here that expression of human uPAR in growing murine fibroblasts leads to a dramatic reorganization of the actin cytoskeleton. uPAR expression induces multiple...

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Hlavní autoři: Kjøller, Lars, Hall, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199201/
https://ncbi.nlm.nih.gov/pubmed/11257116
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