Lipopolysaccharide Induces Disseminated Endothelial Apoptosis Requiring Ceramide Generation

The endotoxic shock syndrome is characterized by systemic inflammation, multiple organ damage, circulatory collapse and death. Systemic release of tumor necrosis factor (TNF)-α and other cytokines purportedly mediates this process. However, the primary tissue target remains unidentified. The present...

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Main Authors: Haimovitz-Friedman, Adriana, Cordon-Cardo, Carlos, Bayoumy, Shariff, Garzotto, Mark, McLoughlin, Maureen, Gallily, Ruth, Edwards, Carl K., Schuchman, Edward H., Fuks, Zvi, Kolesnick, Richard
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1997
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199151/
https://ncbi.nlm.nih.gov/pubmed/9382882
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