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A Ceramide-binding C1 Domain Mediates Kinase Suppressor of Ras Membrane Translocation
Genetic and biochemical data support Kinase Suppressor of Ras 1 (KSR1) as a positive regulator of the Ras-Raf-MAPK pathway, functioning as a kinase and/or scaffold to regulate c-Raf-1 activation. Membrane translocation mediated by the KSR1 CA3 domain, which is homologous to the atypical PKC C1 lipid...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
S. Karger AG
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978518/ https://ncbi.nlm.nih.gov/pubmed/19710537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000233248 |
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