A Ceramide-binding C1 Domain Mediates Kinase Suppressor of Ras Membrane Translocation

Genetic and biochemical data support Kinase Suppressor of Ras 1 (KSR1) as a positive regulator of the Ras-Raf-MAPK pathway, functioning as a kinase and/or scaffold to regulate c-Raf-1 activation. Membrane translocation mediated by the KSR1 CA3 domain, which is homologous to the atypical PKC C1 lipid...

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Detaylı Bibliyografya
Asıl Yazarlar: Yin, Xianglei, Zafrullah, Mohammad, Lee, Hyunmi, Haimovitz-Friedman, Adriana, Fuks, Zvi, Kolesnick, Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: S. Karger AG 2009
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978518/
https://ncbi.nlm.nih.gov/pubmed/19710537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000233248
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