Inhibition of poly (ADP-ribose) Synthetase Attenuates Neutrophil Recruitment and Exerts Antiinflammatory Effects

A cytotoxic cycle triggered by DNA single-strand breakage and poly (ADP-ribose) synthetase activation has been shown to contribute to the cellular injury during various forms of oxidant stress in vitro. The aim of this study was to investigate the role of poly (ADP-ribose) synthetase (PARS) in the p...

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Main Authors: Szabó, Csaba, Lim, Lina H.K., Cuzzocrea, Salvatore, Getting, Stephen J., Zingarelli, Basilia, Flower, Roderick J., Salzman, Andrew L., Perretti, Mauro
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199068/
https://ncbi.nlm.nih.gov/pubmed/9314553
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