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Inhibition of poly (ADP-ribose) Synthetase Attenuates Neutrophil Recruitment and Exerts Antiinflammatory Effects

A cytotoxic cycle triggered by DNA single-strand breakage and poly (ADP-ribose) synthetase activation has been shown to contribute to the cellular injury during various forms of oxidant stress in vitro. The aim of this study was to investigate the role of poly (ADP-ribose) synthetase (PARS) in the p...

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Detalhes bibliográficos
Main Authors: Szabó, Csaba, Lim, Lina H.K., Cuzzocrea, Salvatore, Getting, Stephen J., Zingarelli, Basilia, Flower, Roderick J., Salzman, Andrew L., Perretti, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199068/
https://ncbi.nlm.nih.gov/pubmed/9314553
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