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Effect of L-buthionine-(S,R)-sulphoximine, an inhibitor of γ-glutamylcysteine synthetase on peroxynitrite- and endotoxic shock-induced vascular failure

1. Peroxynitrite, a cytotoxic oxidant formed from the reaction of nitric oxide (NO) and superoxide is a mediator of cellular injury in ischaemia/reperfusion injury, shock and inflammation. Here we investigated whether L-buthionine-(S,R)-sulphoximine (BSO), an inhibitor of γ-glutamylcysteine syntheta...

詳細記述

保存先:
書誌詳細
主要な著者: Cuzzocrea, Salvatore, Zingarelli, Basilia, O'Connor, Michael, Salzman, Andrew L, Szabó, Csaba
フォーマット: Artigo
言語:Inglês
出版事項: 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565175/
https://ncbi.nlm.nih.gov/pubmed/9504394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701612
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