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Ku70 Is Required for DNA Repair but Not for T Cell Antigen Receptor Gene Recombination In Vivo

Ku is a complex of two proteins, Ku70 and Ku80, and functions as a heterodimer to bind DNA double-strand breaks (DSB) and activate DNA-dependent protein kinase. The role of the Ku70 subunit in DNA DSB repair, hypersensitivity to ionizing radiation, and V(D)J recombination was examined in mice that l...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ouyang, Honghai, Nussenzweig, Andre, Kurimasa, Akihiro, Soares, Vera da Costa, Li, Xiaoling, Cordon-Cardo, Carlos, Li, Wen-hui, Cheong, Nge, Nussenzweig, Michel, Iliakis, George, Chen, David J., Li, Gloria C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199057/
https://ncbi.nlm.nih.gov/pubmed/9294146
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