Tumor Eradication by Wild-type p53-specific Cytotoxic T Lymphocytes

The tumor suppressor protein p53 is overexpressed in close to 50% of all human malignancies. The p53 protein is therefore an attractive target for immunotherapy. Cytotoxic T lymphocytes (CTLs) recognizing a murine wild-type p53 peptide, presented by the major histocompatibility complex class I molec...

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Main Authors: Vierboom, Michel P.M., Nijman, Hans W., Offringa, Rienk, van der Voort, Ellen I.H., van Hall, Thorbald, van den Broek, Lambert, Fleuren, Gert Jan, Kenemans, Peter, Kast, W. Martin, Melief, Cornelis J.M.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1997
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199025/
https://ncbi.nlm.nih.gov/pubmed/9271585
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