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Viral Infection of Transgenic Mice Expressing a Viral Protein in Oligodendrocytes Leads to Chronic Central Nervous System Autoimmune Disease

One hypothesis for the etiology of central nervous system (CNS) autoimmune disease is that infection by a virus sharing antigenic epitopes with CNS antigens (molecular mimicry) elicits a virus-specific immune response that also recognizes self-epitopes. To address this hypothesis, transgenic mice we...

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Detalhes bibliográficos
Main Authors: Evans, Claire F., Horwitz, Marc S., Hobbs, Monte V., Oldstone, Michael B.A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196376/
https://ncbi.nlm.nih.gov/pubmed/8976191
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