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Primary demyelination in transgenic mice expressing interferon-γ
Ever since the use of interferon-γ to treat patients with multiple sclerosis resulted in enhanced disease, the role of IFN-γ in demyelination has been under question. To address this issue directly, transgenic mice were generated that expressed the cDNA of murine IFN-γ in the central nervous system...
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| Pubblicato in: | Nat Med |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group US
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321678/ https://ncbi.nlm.nih.gov/pubmed/9288735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm0997-1037 |
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