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Replacement of Pre-T Cell Receptor Signaling Functions by the CD4 Coreceptor

An important checkpoint in early thymocyte development ensures that only thymocytes with an in-frame T cell receptor for antigen β (TCR-β) gene rearrangement will continue to mature. Proper assembly of the TCR-β chain into the pre-TCR complex delivers signals through the src-family protein tyrosine...

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Détails bibliographiques
Auteurs principaux: Norment, Anne M., Forbush, Katherine A., Nguyen, Nhan, Malissen, Marie, Perlmutter, Roger M.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196103/
https://ncbi.nlm.nih.gov/pubmed/8996248
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