Bcl-2 Cooperates with Promyelocytic Leukemia Retinoic Acid Receptor α Chimeric Protein (Pmlrarα) to Block Neutrophil Differentiation and Initiate Acute Leukemia

The promyelocytic leukemia retinoic acid receptor α (PMLRARα) chimeric protein is associated with acute promyelocytic leukemia (APL). PMLRARα transgenic mice develop leukemia only after several months, suggesting that PMLRARα does not by itself confer a fully malignant phenotype. Suppression of apop...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kogan, Scott C., Brown, Diane E., Shultz, David B., Truong, Bao-Tran H., Lallemand-Breitenbach, Valerie, Guillemin, Marie-Claude, Lagasse, Eric, Weissman, Irving L., Bishop, J. Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2001
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195904/
https://ncbi.nlm.nih.gov/pubmed/11181704
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