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The Trypanosoma cruzi trans-Sialidase, through Its Cooh-Terminal Tandem Repeat, Upregulates Interleukin 6 Secretion in Normal Human Intestinal Microvascular Endothelial Cells and Peripheral Blood Mononuclear Cells

The Trypanosoma cruzi trans-sialidase can sensitize mice to become highly susceptible to T. cruzi invasion, through mechanisms that remain unknown. In pursuing this observation, we found that purified trans-sialidase induces the selective release of biologically active interleukin (IL)-6 in naive hu...

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Detalhes bibliográficos
Main Authors: Saavedra, Emma, Herrera, Macario, Gao, Wenda, Uemura, Haruki, Pereira, Miercio A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195715/
https://ncbi.nlm.nih.gov/pubmed/10601357
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