NMR structure of an α-L-LNA:RNA hybrid: structural implications for RNase H recognition

α-L-LNA (α-L-ribo configured locked nucleic acid) is a nucleotide analogue that raises the thermostability of nucleic acid duplexes by up to ∼4°C per inclusion. We have determined the NMR structure of a nonamer α-L-LNA:RNA hybrid with three α-L-LNA modifications. The geometry of this hybrid is inter...

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Bibliografische gegevens

Gepubliceerd in:	Nucleic Acids Res
Hoofdauteurs:	Nielsen, Jakob T., Stein, Paul C., Petersen, Michael
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Oxford University Press 2003
Onderwerpen:	Articles
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC219478/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14530434/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg800
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