The solution structure of a DNA·RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications

The addition of the propynyl group at the 5 position of pyrimidine nucleotides is highly stabilising. We have determined the thermodynamic stability of the DNA·RNA hybrid r(GAAGAGAAGC)·d(GC(p)U(p)U(p)C(p)U(p) C(p)U(p)U(p)C) where p is the propynyl group at the 5 position and compared it with that of...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Gyi, Jeffrey I., Gao, Daquan, Conn, Graeme L., Trent, John O., Brown, Tom, Lane, Andrew N.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2003
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156038/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12736318/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg356
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