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The solution structure of a DNA·RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications

The addition of the propynyl group at the 5 position of pyrimidine nucleotides is highly stabilising. We have determined the thermodynamic stability of the DNA·RNA hybrid r(GAAGAGAAGC)·d(GC(p)U(p)U(p)C(p)U(p) C(p)U(p)U(p)C) where p is the propynyl group at the 5 position and compared it with that of...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Gyi, Jeffrey I., Gao, Daquan, Conn, Graeme L., Trent, John O., Brown, Tom, Lane, Andrew N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2003
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12736318/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg356
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