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IκB Kinase Signaling Is Essential for Maintenance of Mature B Cells
Nuclear factor (NF)-κB proteins play crucial roles in immune responses and cellular survival. Activation of NF-κB is mediated by the IκB kinase (IKK) complex, which is composed of two kinases, IKK1 and IKK2, and a regulatory subunit termed NF-κB essential modulator (NEMO). IKK2- and NEMO-deficient m...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194059/ https://ncbi.nlm.nih.gov/pubmed/12235208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020907 |
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