Iκb Kinase α Is Essential for Mature B Cell Development and Function

IκB kinase (IKK) α and β phosphorylate IκB proteins and activate the transcription factor, nuclear factor (NF)-κB. Although both are highly homologous kinases, gene targeting experiments revealed their differential roles in vivo. IKKα is involved in skin and limb morphogenesis, whereas IKKβ is essen...

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Detalhes bibliográficos
Main Authors: Kaisho, Tsuneyasu, Takeda, Kiyoshi, Tsujimura, Tohru, Kawai, Taro, Nomura, Fumiko, Terada, Nobuyuki, Akira, Shizuo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195900/
https://ncbi.nlm.nih.gov/pubmed/11181694
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