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Localization of the Adhesion Receptor Glycoprotein Ib-IX-V Complex to Lipid Rafts Is Required for Platelet Adhesion and Activation

The platelet glycoprotein (GP) Ib-IX-V complex mediates the attachment of platelets to the blood vessel wall by binding von Willebrand factor (VWF), an interaction that also transmits signals for platelet activation and aggregation. Because the complex is extensively palmitoylated, a modification kn...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shrimpton, Corie N., Borthakur, Gautam, Larrucea, Susana, Cruz, Miguel A., Dong, Jing-Fei, López, José A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194038/
https://ncbi.nlm.nih.gov/pubmed/12391017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020143
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