Glycoprotein Ib-IX-V Complex Transmits Cytoskeletal Forces That Enhance Platelet Adhesion

Platelets bind to exposed vascular matrix at a wound site through a highly specialized surface receptor, glycoprotein (GP) Ib-IX-V complex, which recognizes von Willebrand factor (VWF) in the matrix. GPIb-IX-V is a catch bond for it becomes more stable as force is applied to it. After attaching to t...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Feghhi, Shirin, Munday, Adam D., Tooley, Wes W., Rajsekar, Shreya, Fura, Adriane M., Kulman, John D., López, Jose A., Sniadecki, Nathan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2016
Soggetti:
Cell Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982925/
https://ncbi.nlm.nih.gov/pubmed/27508443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.06.023
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