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Localization of the Adhesion Receptor Glycoprotein Ib-IX-V Complex to Lipid Rafts Is Required for Platelet Adhesion and Activation

The platelet glycoprotein (GP) Ib-IX-V complex mediates the attachment of platelets to the blood vessel wall by binding von Willebrand factor (VWF), an interaction that also transmits signals for platelet activation and aggregation. Because the complex is extensively palmitoylated, a modification kn...

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Detalhes bibliográficos
Main Authors: Shrimpton, Corie N., Borthakur, Gautam, Larrucea, Susana, Cruz, Miguel A., Dong, Jing-Fei, López, José A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194038/
https://ncbi.nlm.nih.gov/pubmed/12391017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020143
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