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Essential Immunoregulatory Role for BCAP in B Cell Development and Function
BCAP was recently cloned as a binding molecule to phosphoinositide 3-kinase (PI3K). To investigate the role of BCAP, mutant mice deficient in BCAP were generated. While BCAP-deficient mice are viable, they have decreased numbers of mature B cells and B1 B cell deficiency. The mice produce lower tite...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193770/ https://ncbi.nlm.nih.gov/pubmed/11877477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011751 |
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