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Essential Immunoregulatory Role for BCAP in B Cell Development and Function

BCAP was recently cloned as a binding molecule to phosphoinositide 3-kinase (PI3K). To investigate the role of BCAP, mutant mice deficient in BCAP were generated. While BCAP-deficient mice are viable, they have decreased numbers of mature B cells and B1 B cell deficiency. The mice produce lower tite...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yamazaki, Tetsuo, Takeda, Kiyoshi, Gotoh, Kumiko, Takeshima, Hiroshi, Akira, Shizuo, Kurosaki, Tomohiro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193770/
https://ncbi.nlm.nih.gov/pubmed/11877477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011751
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