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Genetic Modifiers of Systemic Lupus Erythematosus in FcγRIIB(−/−) Mice

FcγRIIB is a potent lupus susceptibility gene as demonstrated by the observation that mice deficient in this molecule develop spontaneous antinuclear antibodies (ANA) and fatal glomerulonephritis when on the C57BL/6 background. To determine the mechanisms underlying the epistasis displayed by this g...

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Main Authors: Bolland, Silvia, Yim, Young-Sun, Tus, Katalin, Wakeland, Edward K., Ravetch, Jeffrey V.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193704/
https://ncbi.nlm.nih.gov/pubmed/11994421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020165
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