Interferon Regulatory Factor 5 Is Required For Disease Development In The FcγRIIB(−/−)Yaa and FcγRIIB(−/−) Mouse Models Of Systemic Lupus Erythematosus

Polymorphisms in the transcription factor interferon regulatory factor 5 (IRF5) are strongly associated in human genetic studies with an increased risk of developing the autoimmune disease systemic lupus erythematosus. However, the biological role of IRF5 in lupus pathogenesis has not previously bee...

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Main Authors: Richez, Christophe, Yasuda, Kei, Bonegio, Ramon G., Watkins, Amanda A., Aprahamian, Tamar, Busto, Patricia, Richards, Rocco J., Liu, Chih Long, Cheung, Regina, Utz, Paul J., Marshak-Rothstein, Ann, Rifkin, Ian R.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858062/
https://ncbi.nlm.nih.gov/pubmed/20007534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901748
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