Interferon Regulatory Factor 5 Is Required For Disease Development In The FcγRIIB(−/−)Yaa and FcγRIIB(−/−) Mouse Models Of Systemic Lupus Erythematosus

Polymorphisms in the transcription factor interferon regulatory factor 5 (IRF5) are strongly associated in human genetic studies with an increased risk of developing the autoimmune disease systemic lupus erythematosus. However, the biological role of IRF5 in lupus pathogenesis has not previously bee...

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Autors principals: Richez, Christophe, Yasuda, Kei, Bonegio, Ramon G., Watkins, Amanda A., Aprahamian, Tamar, Busto, Patricia, Richards, Rocco J., Liu, Chih Long, Cheung, Regina, Utz, Paul J., Marshak-Rothstein, Ann, Rifkin, Ian R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858062/
https://ncbi.nlm.nih.gov/pubmed/20007534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901748
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