CD8β Endows CD8 with Efficient Coreceptor Function by Coupling T Cell Receptor/CD3 to Raft-associated CD8/p56(lck) Complexes

The extraordinary sensitivity of CD8(+) T cells to recognize antigen impinges to a large extent on the coreceptor CD8. While several studies have shown that the CD8β chain endows CD8 with efficient coreceptor function, the molecular basis for this is enigmatic. Here we report that cell-associated CD...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Arcaro, Alexandre, Grégoire, Claude, Bakker, Talitha R., Baldi, Lucia, Jordan, Martin, Goffin, Laurence, Boucheron, Nicole, Wurm, Florian, van der Merwe, P. Anton, Malissen, Bernard, Luescher, Immanuel F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2001
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193676/
https://ncbi.nlm.nih.gov/pubmed/11714755
Tagiau: Ychwanegu Tag
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