The Production of a New MAGE-3 Peptide Presented to Cytolytic T Lymphocytes by HLA-B40 Requires the Immunoproteasome

By stimulating human CD8(+) T lymphocytes with autologous dendritic cells infected with an adenovirus encoding MAGE-3, we obtained a cytotoxic T lymphocyte (CTL) clone that recognized a new MAGE-3 antigenic peptide, AELVHFLLL, which is presented by HLA-B40. This peptide is also encoded by MAGE-12. T...

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Autores principales: Schultz, Erwin S., Chapiro, Jacques, Lurquin, Christophe, Claverol, Stéphane, Burlet-Schiltz, Odile, Warnier, Guy, Russo, Vincenzo, Morel, Sandra, Lévy, Frédéric, Boon, Thierry, Van den Eynde, Benoît J., van der Bruggen, Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2002
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193621/
https://ncbi.nlm.nih.gov/pubmed/11854353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011974
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