A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3

Vaccination of melanoma patients with tumor-specific antigens recognized by cytolytic T lymphocytes (CTL) produces significant tumor regressions in a minority of patients. These regressions appear to occur in the absence of massive CTL responses. To detect low-level responses, we resorted to antigen...

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Main Authors: Coulie, Pierre G., Karanikas, Vaios, Colau, Didier, Lurquin, Christophe, Landry, Claire, Marchand, Marie, Dorval, Thierry, Brichard, Vincent, Boon, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC56954/
https://ncbi.nlm.nih.gov/pubmed/11517302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161260098
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