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Role for Mismatch Repair Proteins Msh2, Mlh1, and Pms2 in Immunoglobulin Class Switching Shown by Sequence Analysis of Recombination Junctions

B cells from mice deficient in mismatch repair (MMR) proteins show decreased ability to undergo class switch recombination in vitro and in vivo. The deficit is not accompanied by any reduction in cell viability or alterations in the cell cycle in B cells cultured in vitro. To assess the role of MMR...

詳細記述

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書誌詳細
主要な著者: Schrader, Carol E., Vardo, Joycelyn, Stavnezer, Janet
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193596/
https://ncbi.nlm.nih.gov/pubmed/11828012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011877
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