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Involvement of the TCR Cβ FG Loop in Thymic Selection and T Cell Function
The asymmetric disposition of T cell receptor (TCR) Cβ and Cα ectodomains creates a cavity with a side-wall formed by the rigid Cβ FG loop. To investigate the significance of this conserved structure, we generated loop deletion (βΔFG) and βwt transgenic (tg) mice using the TCR β subunit of the N15 C...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193539/ https://ncbi.nlm.nih.gov/pubmed/12045240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020119 |
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