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One of the CD3ε Subunits within a T Cell Receptor Complex Lies in Close Proximity to the Cβ FG Loop

A recent crystal structure of the N15 α/β-T cell receptor (TCR) in complex with an Fab derived from the H57 Cβ-specific monoclonal antibody (mAb) shows the mAb fragment interacting with the elongated FG loop of the Cβ domain. This loop creates one side wall of a cavity within the TCR Ti-α/β constant...

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Detalhes bibliográficos
Main Authors: Ghendler, Yoseph, Smolyar, Alex, Chang, Hsiu-Ching, Reinherz, Ellis L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212265/
https://ncbi.nlm.nih.gov/pubmed/9565644
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