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Involvement of the TCR Cβ FG Loop in Thymic Selection and T Cell Function

The asymmetric disposition of T cell receptor (TCR) Cβ and Cα ectodomains creates a cavity with a side-wall formed by the rigid Cβ FG loop. To investigate the significance of this conserved structure, we generated loop deletion (βΔFG) and βwt transgenic (tg) mice using the TCR β subunit of the N15 C...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sasada, Tetsuro, Touma, Maki, Chang, Hsiu-Ching, Clayton, Linda K., Wang, Jia-huai, Reinherz, Ellis L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193539/
https://ncbi.nlm.nih.gov/pubmed/12045240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020119
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