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Complement 1 Inhibitor Is a Regulator of the Alternative Complement Pathway

We studied complement 1 inhibitor (C1-INH) as an inhibitor of the alternative complement pathway. C1-INH prevented lysis, induced by the alternative complement pathway, of paroxysmal nocturnal hemoglobinuria (PNH) erythrocytes in human serum. It inhibited the binding of both factors B and C3 to PNH...

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Detalhes bibliográficos
Main Authors: Jiang, Haixiang, Wagner, Eric, Zhang, Huamei, Frank, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193533/
https://ncbi.nlm.nih.gov/pubmed/11733575
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