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Heparan Sulfate, Including that in Bruch’s Membrane, Inhibits the Complement Alternative Pathway: Implications for Age-related Macular Degeneration
An imbalance between activation and inhibition of the complement system has been implicated in the etiologies of numerous common diseases. Allotypic variants of a key complement fluid phase regulatory protein, complement factor H (CFH), are strongly associated with age-related macular degeneration (...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3639479/ https://ncbi.nlm.nih.gov/pubmed/20876352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903596 |
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