C-Rel Regulates Interleukin 12 P70 Expression in Cd8(+) Dendritic Cells by Specifically Inducing p35 Gene Transcription

Interleukin 12 (IL-12) is a 70-kD proinflammatory cytokine produced by antigen presenting cells that is essential for the induction of T helper type 1 development. It comprises 35-kD (p35) and 40-kD (p40) polypeptides encoded by separate genes that are induced by a range of stimuli that include lipo...

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Detalhes bibliográficos
Main Authors: Grumont, Raelene, Hochrein, Hubertus, O'Keeffe, Meredith, Gugasyan, Raffi, White, Christine, Caminschi, Irina, Cook, Wendy, Gerondakis, Steve
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193517/
https://ncbi.nlm.nih.gov/pubmed/11602633
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