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Immunosuppression and Resultant Viral Persistence by Specific Viral Targeting of Dendritic Cells

Among cells of the immune system, CD11c(+) and DEC-205(+) splenic dendritic cells primarily express the cellular receptor (α-dystroglycan [α-DG]) for lymphocytic choriomeningitis virus (LCMV). By selection, strains and variants of LCMV that bind α-DG with high affinity are associated with virus repl...

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Detalhes bibliográficos
Main Authors: Sevilla, Noemí, Kunz, Stefan, Holz, Andreas, Lewicki, Hanna, Homann, Dirk, Yamada, Hiroki, Campbell, Kevin P., de la Torre, Juan C., Oldstone, Michael B.A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193355/
https://ncbi.nlm.nih.gov/pubmed/11067874
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