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Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion

DCs play a pivotal role in bringing forth innate and adaptive immune responses. Viruses can specifically target DCs, rendering them ineffective in stimulating T cells, which can ultimately lead to immunosuppression. In the present study we have identified several potential mechanisms by which lympho...

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Détails bibliographiques
Auteurs principaux: Sevilla, Noemí, McGavern, Dorian B., Teng, Chao, Kunz, Stefan, Oldstone, Michael B.A.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC351322/
https://ncbi.nlm.nih.gov/pubmed/14991072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420243
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