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Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion
DCs play a pivotal role in bringing forth innate and adaptive immune responses. Viruses can specifically target DCs, rendering them ineffective in stimulating T cells, which can ultimately lead to immunosuppression. In the present study we have identified several potential mechanisms by which lympho...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC351322/ https://ncbi.nlm.nih.gov/pubmed/14991072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420243 |
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