Lymphotoxin-α- and Lymphotoxin-β-Deficient Mice Differ in Susceptibility to Scrapie: Evidence against Dendritic Cell Involvement in Neuroinvasion

Transmissible spongiform encephalopathy or prion diseases are fatal neurodegenerative disorders of humans and animals often initiated by oral intake of an infectious agent. Current evidence suggests that infection occurs initially in the lymphoid tissues and subsequently in the central nervous syste...

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Detalhes bibliográficos
Main Authors: Oldstone, Michael B. A., Race, Richard, Thomas, Diane, Lewicki, Hanna, Homann, Dirk, Smelt, Sara, Holz, Andreas, Koni, Pandelakis, Lo, David, Chesebro, Bruce, Flavell, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155094/
https://ncbi.nlm.nih.gov/pubmed/11932402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.9.4357-4363.2002
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